Clinical Management Following Multi-Cancer Early Detection Testing
In the fourth and final video of this series, PA Sarah Enslin walks through a patient case to demonstrate how to manage a positive multi-cancer early detection (MCED) test result in practice. Tania, a 58-year-old with a strong family history of breast and pancreatic cancer, receives a positive MCED result without a predicted cancer origin. PA Enslin explains her clinical reasoning for additional screening based on Tania’s personal risk profile and describes how collaborating with oncology and genetics colleagues shaped the follow-up plan.
Key Takeaways:
- Currently available multi-cancer early detection tests give a qualitative “positive” or “negative” result.
- Medical and family history can be weighed alongside positive multi-cancer early detection test results to determine the path forward for each patient.
- Establish relationships and a workflow that enables optimal patient care when starting to use multi-cancer early detection tests.
Speaker
Click on the photo below to learn more about the speaker.
References and Additional Resources:
Abbott. Cancerguard Test Provider Resources. Accessed August 3, 2026. https://www.exactsciences.com/cancer-testing/cancerguard-mced-providers/resources
Angelis GI, Ockenden K, Meikle SR, Calamante F. Managing incidental findings in total body PET/CT studies: balancing ethical considerations and resource constraints. EJNNMI Rep. 2025;9(1):18. https://pmc.ncbi.nlm.nih.gov/articles/PMC12095698/
Galleri. Provider Overview. Accessed August 3, 2026. http://galleri.com/hcp
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