Stages of Alzheimer’s Disease: Understanding Functional Loss and Care Over Time

In this video, PA Klingler explains the clinical staging of Alzheimer’s disease and how understanding these stages enables PAs to align care plans, interventions, and referrals with patients’ changing needs. She introduces the Alzheimer’s Association’s 2024 staging guidelines and simplifies the seven-stage clinical model into three clear categories: mild, moderate, and severe dementia.

Key Takeaways:

  1. Alzheimer’s disease is divided into 6 stages. Patients have specific needs in each stage.
  2. Earlier stages provide opportunities for pharmacological intervention.
  3. Later stages become increasingly difficult for care partners.

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References and Additional Resources:

Alzheimer’s stages: How the disease progresses. Mayo Clinic. Accessed July 23, 2025. https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/in-depth/alzheimers-stages/art-20048448

Jack CR Jr, Andrews JS, Beach TG, et al. Revised criteria for diagnosis and staging of Alzheimer’s disease: Alzheimer’s Association Workgroup. Alzheimers Dement. 2024;20(8):5143-5169. doi:10.1002/alz.13859

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