Basal Insulin and Patient Conversations
PA Orr focuses on how to talk with patients about starting weekly basal insulin. She explains how she sets expectations on efficacy based on the ONWARDS and QWINT trial programs and how she addresses common concerns such as hypoglycemia and weight gain.
She also walks through practical topics: injection training, reminders, titration, follow-up, and what to do about missed doses. PA Orr closes by explaining how her care team has fit weekly insulin into its existing diabetes workflows.
Key Takeaways:
- Data supports the likelihood of treatment success is not compromised with weekly insulin vs daily insulin.
- Any insulin treatment comes with a risk of hypoglycemia, and PAs should educate patients on how to detect and respond.
- Titration of weekly insulin is guided by blood glucose monitoring, similar to daily insulin.
Speaker
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References and Additional Resources:
AWIQLI. Prescribing Information. Novo Nordisk, Inc.; 2026. https://www.novo-pi.com/awiqli.pdf
Forst T, Choudhary P, Schneider D, Linetzky B, Pozzilli P. A practical approach to the clinical challenges in initiation of basal insulin therapy in people with type 2 diabetes. Diabetes Metab Res Rev. 2021;37(6):e3418. https://pmc.ncbi.nlm.nih.gov/articles/PMC8519070/
ONSWIK. Prescribing Information. Eli Lilly and Company. 2026. https://uspl.lilly.com/onswik/onswik.html#pi
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